Jonas Pielenhofer

Contact

Room: 03-164

E-Mail: jpielenh@uni-mainz.de

Phone: +49 6131 39 29563

Position

PhD student/ Research Assistant

Fields of research

Development of novel formulations for transcutaneous vaccination i.e. nano- and microemulsions and microneedle-based formulations

Manufacture and supply of an investigational medicinal product (IMP) being investigated for the treatment of actinic keratosis (AK) in an open labeled, randomized, phase II clinical regarding tolerability (primary endopoint), safety, efficacy, compliance, cosmetic outcome and patient quality of life, DQLI (secondary endpoints). EudraCT number 2015-002203-28

Publications

  • Schmidt, P. C., Lang, S., Pielenhofer, J. (2020). Pharmazeutische Hilfsstoffe - Eigenschaften, Anwendung und Handelsprodukte (Vol. 2). Eschborn, Germany: Govi Verlag.

Journal Articles

  • Pielenhofer J, Meiser SL, Gogoll K, Ciciliani A-M, Klak M, Lang BM, Staubach P, Grabbe S, Schild H, Radsak MP, Spahn-Langguth H, Langguth P. Complaint management of a quality defect in a nanoparticulate Imiquimod formulation in an investigator initiated academic phase I/II clinical trial. Pharm. Ind. 85, Nr. 2 182-186(2023)
  • Pielenhofer J, Meiser SL, Gogoll K, Ciciliani A-M, Denny M, Klak M, Lang BM, Staubach P, Grabbe S, Schild H, Radsak MP, Spahn-Langguth H, Langguth P. Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product. Pharmaceutics. 2023; 15(2):514. https://doi.org/10.3390/pharmaceutics15020514
  • Pielenhofer J, Sohl J, Windbergs M, Langguth P, Radsak MP. (2020). Current Progress in Particle-Based Systems for Transdermal Vaccine Deliver. Front Immunol. 11:266. doi 10.3389/fimmu.2020.00266.

Other activities

  • Teaching: Supervision of undergraduate pharmacy students (7th semester) for practical exercises and theory for dispersions including emulsions & suspensions; semisolids and rheology; suppositories; liposomes, nanoparticles and transdermal therapeutic systems; responsible for oral and written exams,
  • Participating in the MAS program Translational Medicine & Biomedical Entrepreneurship at sitem insel AG, Bern, Switzerland