Doctoral dissertations

 

Jonas Pielenhofer (2017-2023)

"Quality, safety and efficacy of a novel nanoparticulate imiquimod formulation"

Michael Klak (2016-2023)

"Magnetische Polymernanopartikel - Charakterisierung und Effizienzsteigerung von superparamagnetischem Eisenoxid in Polymernanokapseln, sowie niederfrequente magnetische Freisetzung"

Birhanu Nigusse Kahsay (2023)

"Formulation and characterization of colloidal formulations loaded with free amino acids for dermal delivery"

Sara S. Nogueira (2016 – 2023)

"Next generation Lipid Nanoparticles for mRNA delivery"

Lukas Uebbing (2017-2022)

"Structural and Functional Characterization of Lipid-based mRNA Delivery Systems"

Moritz Rosch (2018-2022)

"A novel effervescent hydrogen-generating tablet – formulation, optimization and in-depth characterization"

Mauricio Garcia (2018-2022)

"Biopharmaceutic Prediction of Oral Absorption from Immediate Release Dosage Forms"

Johannes Blechar (2017-2022)

"Biopredictive disintegration and dissolution of solid oral dosage forms"

Adrian Strobel (2017-2021)

"Solubilization Strength Characterization of Parenteral Solutions Containing Polysorbate 80 in Support of Extractable & Leachable Studies"

Michael Hofmann (2016-2021)

"Toward biopredictive dissolution testing of BCS class II acids: insights into in vivo and in vitro dissolution of poorly soluble ionizable actives"

Mark Denny (2014-2020)

"Pharmaceutical characterization of imiquimod formulations for dermal immunization"

Maoqi Fu (2016-2020)

"Enteric coated HPMC capsules: Comparison of enteric coatings and investigation of relationship between disintegration and dissolution times"

Philipp Gattig (2017-2020)

"Entwicklung eines Computer-gestützten Ansatzes zur Verknüpfung von Qualitätsattributen und Prozessparametern unter Verwendung von maschinellem Lernen"

Christian Siewert (2015-2019)

"Pharmaceutical development of polyplex-based mRNA delivery systems"

Antje Ziller (2015-2019)

"Structural and functional characterization of lipoplexes for tumor vaccination"

Anke Heinrich (2015-2019)

"Interplay between autoinjector device and viscous protein formulations for subcutaneous administration"

Julia Schnorr (2014-2018)

"Charakterisierung parenteraler Eisenkomplexe: Untersuchungen zu Physikochemie, in-vitro-Verhalten und Austauschbarkeit von Eisen „non-biological complex drugs“"

Kamran Zaheer (2014-2018)

"Evaluation of formulation and processing factors on the disintegration and dissolution of immediate release tablets in fed state: Formulation strategy towards minimizing viscosity-mediated negative food effect"

Deborah Bickmann (2005-2017)

"Modelling the performance of inhalation devices in adults and children: Development and evaluation of new in vitro and in silico models"

Kristin Forner (2013-2017)

"Formulation effects on oral drug absorption: Key parameters for the biopredictivity of dissolution/permeation experiments"

Jayachandar Gajendran (2007-2017)

"Performance testing of medicated chewing gums with the goal of establishing in vitro in vivo correlations"

Anna Maria Ciciliani (2012-2017)

"Pharmazeutische Aerosole für pädiatrische und geriatrische Patienten"

Maartje Elizabeth Kubbinga (2009-2016)

"BCS-based biowaivers:risks and opportunities"

Jozef Al-Gousous (2013-2016)

"Tackling the obstacles to developing enteric-coated dosage forms with quick post-gastric emptying disintegration"

Matthias Manne Knopp (2012-2016)

"Development of predictive tools for amorphous solid dosage forms"

Julian Schichtel (2011-2016)

"Determination of the dissolution behavior of celecoxib-Eudragit E 100-nanoparticles using cross-flow filtration"

Daniel Frache (2009-2016)

"Untersuchung von Einflussparametern auf die Spray-Performance des Respimat Soft Mist Inhalers"

Sebastian Trebbien (2011-2016)

"Entwicklung eines Simulationsmodells für das Life-Cycle-Management von Arzneimitteln"

Pooneh Khoshakhlagh (2012-2015)

"FaSSIF-C, a cholesterol containing biorelevant intestinal model medium for development and test of oral drug formulations"

Raphael Johnson (2012-2015)

"Amphotericin B Nano-formulations: Development, characterization and suitability for oral administration"

Mai Anh Nguyen (2011-2015)

"The influence of quercetin and naringin on drug transport and metabolism in humans – Implications for the evaluation of neutraceutical-drug interactions"

Sarah Kindgen (2012-2015)

"Hydrodynamics and solid dosage form disintegration/dissolution: Immediate release tablets and novel in situ polyelectrolyte gastroretentive drug delivery systems"

Kathrin Gerlich (2012-2015)

"Entwicklung einer neuen Wassergehaltsbestimmungs-methode für feste Arzneiformen mittels elektrischer Leitfähigkeit"

Emre Türelli (2008-2015)

"Nanoparticle preparation process using novel microjet reactor technology for enhancing dissolution rates of poorly water soluble drugs"

Karsten Gogoll (2010-2014)

"JOGU: Imiquimod based transcutaneous immunization – insights and novel concepts"

Sören Fütterer (2009-2014)

"JOGU: Nanoparticular iron complex drugs for parenteral administration – Physicochemical characterization, biological distribution and pharmacological safety"

Simon Geißler (2008-2014)

"JOGU: Small scale processing of nanoscopic formulations for preclinical development of poorly soluble compounds"

Tanja Peters (2007-2013)

"JOGU: Development and in vitro testing of liposomal gadolinium formulations for neutron capture therapy of glioblastoma multiforme"

Eva Hühn (2008-2013)

"JOGU: Rational design of sustained release liposomal mRNA formulations for parenteral administration and image-guided assessment of in vivo performance"

Robert Winkler (2010-2013)

"JOGU: Konzept eines aktiven Pulverinhalators"

Asma Abdelaziz Salim Radwan (2009-2013)

"JOGU: Biopharmaceutic investigation of negative food effect for BCS class III compounds in solid dosage forms"

Zuheir Abdelrahman Elawad Osman (2009-2012)

"JOGU: Investigation of different shellac grades and improvement of release from air suspension coated pellets"

Karl Buch (2005-2011)

"JOGU: Lanthanide-loaded nanoparticles as a novel radioenhancer in radiation therapy of cancer"

Lukas Mühlfeld (2008-2011)

"JOGU: Einflüsse von Folienqualität und Blister-Design auf die Funktionalität von Blisterverpackungen"

Andrea Hartung (2008-2011)

"JOGU: Prozess Analytische Technologien „PAT“ zur Optimierung von Wirbelschichtgranulationsprozessen"

Olga Pfeifer-Lehmann (2006-2010)

"JOGU: Untersuchung der Adhäsionskräfte in interaktiven Pulvermischungen zur Inhalation und deren Veränderung in Abhängigkeit von der Dichtigkeit der Verpackung"

Markus Jahn (2004–2009)

"JOGU: Struktur, Stabilität, Toxizität und zelluläre Aufnahme von Eisenoxid- und Eisenhydroxid Nanopartikeln"

Gamal Shazly (2005-2009)

"JOGU: Effect of drug physicochemical properties on the release from liposomal systems in vitro and in vivo"

Stefan Grube (2005-2008)

"JOGU: Excipient- and food-drug interactions with spezial emphasis on trospium"

Claudius Weiler (2004-2008)

"JOGU: Generierung leicht dispergierbarer Inhalationspulver mittels Sprühtrocknung"

Natalie Devi Glube, (2001-2007)

"JOGU: The potential of the human kidney cell line Caki-1, as an in vitro sceening system for drug interactions with organic cation transporters"

N. Ceren Alemdaroglu (2004-2007)

"JOGU: Impact of folate absorption and transport for nutrition and drug targeting"

Marija Tubic-Grozdanis (2003-2007)

"JOGU: Biopharmaceutical characterization of modified-release dosage forms of P-glycoprotein and CYP 3A4 substrates in silico and in humans"

Torsten Mau (1999-2006)

"JOGU: Entwicklung und Charakterisierung von Gassterilisationsprozessen am Beispiel der Oberflächensterilisation mittels Wasserstoffperoxid und Ethylenoxid"

Isabell Andrea Schöttle (2001-2005)

"JOGU: Sprühgetrocknete Polylaktid, Poly(Laktid-co-glycolid) Mikropartikel zur Steuerung der Freisetzung aus pulmonalen Arzneiformen"

Marcus Hans Knöll (2002-2006)

"JOGU: Enteric coated mucoadhesive micropellets in rotary agglomeration process for wet spheronization"

Bianca Beilmann (2003-2006)

"JOGU:Evaluierung und Quantifizierung von Einflussfaktoren auf die aerodynamischen Eigenschaften inhalativer Pulvermischungen"

Monika Ofer (Mainz 2004)

"Modulation of Membrane Transport - A Mechanism to Explain Kinetic Interactions Between Drugs and Flavonoids"

Amal El Saeih Fadl Abou El Ela (Mainz 2003)

"Implications of Physicochemical Parameters for Carrier-Mediated and Passive Membrane Transport for Psychoactive Drugs"

Martin Becker (Mainz 2003)

"Charakterisierung der Arzneistoffabsorption aus flüssigen Externa zur kutanen Anwendung am Tier"

Katharina Brodka-Pfeiffer (Mainz 2003)

"Einfluss von Mikronisierungsprozessen auf die physikochemische Stabilität von Pulvern für Inhalationszwecke. Kriterien für die Auswahl von Konditionierungsparametern."

Daniel Wagner (Mainz 2003)

"Sustained-release formulations for compounds underlying intestinal drug efflux"

Annette Koggel (Mainz 2002)

"Influence of Secretory Transporters on the Intestinal Permeability of Cationic Drugs"