Doctoral dissertations

Kristin Forner (2013-2017) Formulation effects on oral drug absorption: Key parameters for the biopredictivity of dissolution/permeation experiments

Jayachandar Gajendran (2007-2017) Performance testing of medicated chewing gums with the goal of establishing in vitro in vivo correlations

Anna Maria Ciciliani (2012-2017) Pharmazeutische Aerosole für pädiatrische und geriatrische Patienten

Maartje Elizabeth Kubbinga (2009-2016) BCS-based biowaivers: risks and opportunities

Jozef Al-Gousous (2013-2016) Tackling the obstacles to developing enteric-coated dosage forms with quick post-gastric emptying disintegration

Matthias Manne Knopp (2012-2016) Development of predictive tools for amorphous solid dosage forms

Julian Schichtel (2011-2016) Determination of the dissolution behavior of celecoxib-Eudragit E 100-nanoparticles using cross-flow filtration

Daniel Frache (2009-2016) Untersuchung von Einflussparametern auf die Spray-Performance des Respimat Soft Mist Inhalers

Sebastian Trebbien (2011-2016) Entwicklung eines Simulationsmodells für das Life-Cycle-Management von Arzneimitteln

Pooneh Khoshakhlagh (2012-2015) FaSSIF-C, a cholesterol containing biorelevant intestinal model medium for development and test of oral drug formulations

Raphael Johnson (2012-2015) Amphotericin B Nano-formulations: Development, characterization and suitability for oral administration

Mai Anh Nguyen (2011-2015) The influence of quercetin and naringin on drug transport and metabolism in humans – Implications for the evaluation of neutraceutical-drug interactions

Sarah Kindgen (2012-2015) Hydrodynamics and solid dosage form disintegration/dissolution: Immediate release tablets and novel in situ polyelectrolyte gastroretentive drug delivery systems

Kathrin Gerlich (2012-2015) Entwicklung einer neuen Wassergehaltsbestim¬mungs-methode für feste Arzneiformen mittels elektrischer Leitfähigkeit

Emre Türelli (2008-2015) Nanoparticle preparation process using novel microjet reactor technology for enhancing dissolution rates of poorly water soluble drugs

Karsten Gogoll (2010-2014) JOGU: Imiquimod based transcutaneous immunization – insights and novel concepts

Sören Fütterer (2009-2014) JOGU: Nanoparticular iron complex drugs for parenteral administration – Physicochemical characterization, biological distribution and pharmacological safety

Simon Geißler (2008-2014) JOGU: Small scale processing of nanoscopic formulations for preclinical development of poorly soluble compounds

Tanja Peters (2007-2013) JOGU: Development and in vitro testing of liposomal gadolinium formulations for neutron capture therapy of glioblastoma multiforme

Eva Hühn (2008-2013) JOGU: Rational design of sustained release liposomal mRNA formulations for parenteral administration and image-guided assessment of in vivo performance

Robert Winkler (2010-2013) JOGU: Konzept eines aktiven Pulverinhalators

Asma Abdelaziz Salim Radwan (2009-2013) JOGU: Biopharmaceutic investigation of negative food effect for BCS class III compounds in solid dosage forms

Zuheir Abdelrahman Elawad Osman (2009-2012) JOGU: Investigation of different shellac grades and improvement of release from air suspension coated pellets

Karl Buch (2005-2011) JOGU: Lanthanide-loaded nanoparticles as a novel radioenhancer in radiation therapy of cancer

Lukas Mühlfeld (2008-2011) JOGU: Einflüsse von Folienqualität und Blister-Design auf die Funktionalität von Blisterverpackungen

Andrea Hartung (2008-2011) JOGU: Prozess Analytische Technologien „PAT“ zur Optimierung von Wirbelschichtgranulationsprozessen

Olga Pfeifer-Lehmann (2006-2010) JOGU: Untersuchung der Adhäsionskräfte in interaktiven Pulvermischungen zur Inhalation und deren Veränderung in Abhängigkeit von der Dichtigkeit der Verpackung

Markus Jahn (2004 – 2009) JOGU: Struktur, Stabilität, Toxizität und zelluläre Aufnahme von Eisenoxid- und Eisenhydroxid Nanopartikeln

Gamal Shazly (2005-2009) JOGU: Effect of drug physicochemical properties on the release from liposomal systems in vitro and in vivo

Stefan Grube (2005-2008) JOGU: Excipient- and food-drug interactions with spezial emphasis on trospium

Claudius Weiler (2004-2008) JOGU: Generierung leicht dispergierbarer Inhalationspulver mittels Sprühtrocknung

Natalie Devi Glube, (2001-2007) JOGU: The potential of the human kidney cell line Caki-1, as an in vitro sceening system for drug interactions with organic cation transporters

N. Ceren Alemdaroglu (2004-2007) JOGU: Impact of folate absorption and transport for nutrition and drug targeting)

Marija Tubic-Grozdanis (2003-2007) JOGU: Biopharmaceutical characterization of modified-release dosage forms of P-glycoprotein and CYP 3A4 substrates in silico and in humans

Torsten Mau (1999-2006) JOGU: Entwicklung und Charakterisierung von Gassterilisationsprozessen am Beispiel der Oberflächensterilisation mittels Wasserstoffperoxid und Ethylenoxid

Isabell Andrea Schöttle (2001-2005) JOGU: Sprühgetrocknete Polylaktid, Poly(Laktid-co-glycolid) Mikropartikel zur Steuerung der Freisetzung aus pulmonalen Arzneiformen

Marcus Hans Knöll (2002-2006) JOGU: Enteric coated mucoadhesive micropellets in rotary agglomeration process for wet spheronization

Bianca Beilmann (2003-2006) JOGU: Evaluierung und Quantifizierung von Einfluss¬faktoren auf die aerodynamischen Eigenschaften inhalativer Pulvermischungen

Monika Ofer, Mainz 2004: Modulation of Membrane Transport - A Mechanism to Explain Kinetic Interactions Between Drugs and Flavonoids

Amal El Saeih Fadl Abou El Ela, Mainz 2003: Implications of Physicochemical Parameters for Carrier-Mediated and Passive Membrane Transport for Psychoactive Drugs

Martin Becker, Mainz 2003: Charakterisierung der Arzneistoffabsorption aus flüssigen Externa zur kutanen Anwendung am Tier

Katharina Brodka-Pfeiffer, Mainz 2003: Einfluss von Mikronisierungsprozessen auf die physikochemische Stabilität von Pulvern für Inhalationszwecke. Kriterien für die Auswahl von Konditionierungsparametern.

Daniel Wagner, Mainz 2003: Sustained-release formulations for compounds underlying intestinal drug efflux

Annette Koggel, Mainz 2002: Influence of Secretory Transporters on the Intestinal Permeability of Cationic Drugs