Doctoral dissertations

Sara S. Nogueira (2016 – 2023)

"Next generation Lipid Nanoparticles for mRNA delivery"

Lukas Uebbing (2017-2022)

"Structural and Functional Characterization of Lipid-based mRNA Delivery Systems"

Moritz Rosch (2018-2022)

"A novel effervescent hydrogen-generating tablet – formulation, optimization and in-depth characterization"

Mauricio Garcia (2018-2022)

"Biopharmaceutic Prediction of Oral Absorption from Immediate Release Dosage Forms"

Johannes Blechar (2017-2022)

"Biopredictive disintegration and dissolution of solid oral dosage forms"

Adrian Strobel (2017-2021)

"Solubilization Strength Characterization of Parenteral Solutions Containing Polysorbate 80 in Support of Extractable & Leachable Studies"

Michael Hofmann (2016-2021)

"Toward biopredictive dissolution testing of BCS class II acids: insights into in vivo and in vitro dissolution of poorly soluble ionizable actives"

Mark Denny (2014-2020)

"Pharmaceutical characterization of imiquimod formulations for dermal immunization"

Maoqi Fu (2016-2020)

"Enteric coated HPMC capsules: Comparison of enteric coatings and investigation of relationship between disintegration and dissolution times"

Philipp Gattig (2017-2020)

"Entwicklung eines Computer-gestützten Ansatzes zur Verknüpfung von Qualitätsattributen und Prozessparametern unter Verwendung von maschinellem Lernen"

Christian Siewert (2015-2019)

"Pharmaceutical development of polyplex-based mRNA delivery systems"

Antje Ziller (2015-2019)

"Structural and functional characterization of lipoplexes for tumor vaccination"

Anke Heinrich (2015-2019)

"Interplay between autoinjector device and viscous protein formulations for subcutaneous administration"

Julia Schnorr (2014-2018)

"Charakterisierung parenteraler Eisenkomplexe: Untersuchungen zu Physikochemie, in-vitro-Verhalten und Austauschbarkeit von Eisen „non-biological complex drugs“"

Kamran Zaheer (2014-2018)

"Evaluation of formulation and processing factors on the disintegration and dissolution of immediate release tablets in fed state: Formulation strategy towards minimizing viscosity-mediated negative food effect"

Deborah Bickmann (2005-2017)

"Modelling the performance of inhalation devices in adults and children: Development and evaluation of new in vitro and in silico models"

Kristin Forner (2013-2017)

"Formulation effects on oral drug absorption: Key parameters for the biopredictivity of dissolution/permeation experiments"

Jayachandar Gajendran (2007-2017)

"Performance testing of medicated chewing gums with the goal of establishing in vitro in vivo correlations"

Anna Maria Ciciliani (2012-2017)

"Pharmazeutische Aerosole für pädiatrische und geriatrische Patienten"

Maartje Elizabeth Kubbinga (2009-2016)

"BCS-based biowaivers:risks and opportunities"

Jozef Al-Gousous (2013-2016)

"Tackling the obstacles to developing enteric-coated dosage forms with quick post-gastric emptying disintegration"

Matthias Manne Knopp (2012-2016)

"Development of predictive tools for amorphous solid dosage forms"

Julian Schichtel (2011-2016)

"Determination of the dissolution behavior of celecoxib-Eudragit E 100-nanoparticles using cross-flow filtration"

Daniel Frache (2009-2016)

"Untersuchung von Einflussparametern auf die Spray-Performance des Respimat Soft Mist Inhalers"

Sebastian Trebbien (2011-2016)

"Entwicklung eines Simulationsmodells für das Life-Cycle-Management von Arzneimitteln"

Pooneh Khoshakhlagh (2012-2015)

"FaSSIF-C, a cholesterol containing biorelevant intestinal model medium for development and test of oral drug formulations"

Raphael Johnson (2012-2015)

"Amphotericin B Nano-formulations: Development, characterization and suitability for oral administration"

Mai Anh Nguyen (2011-2015)

"The influence of quercetin and naringin on drug transport and metabolism in humans – Implications for the evaluation of neutraceutical-drug interactions"

Sarah Kindgen (2012-2015)

"Hydrodynamics and solid dosage form disintegration/dissolution: Immediate release tablets and novel in situ polyelectrolyte gastroretentive drug delivery systems"

Kathrin Gerlich (2012-2015)

"Entwicklung einer neuen Wassergehaltsbestimmungs-methode für feste Arzneiformen mittels elektrischer Leitfähigkeit"

Emre Türelli (2008-2015)

"Nanoparticle preparation process using novel microjet reactor technology for enhancing dissolution rates of poorly water soluble drugs"

Karsten Gogoll (2010-2014)

"JOGU: Imiquimod based transcutaneous immunization – insights and novel concepts"

Sören Fütterer (2009-2014)

"JOGU: Nanoparticular iron complex drugs for parenteral administration – Physicochemical characterization, biological distribution and pharmacological safety"

Simon Geißler (2008-2014)

"JOGU: Small scale processing of nanoscopic formulations for preclinical development of poorly soluble compounds"

Tanja Peters (2007-2013)

"JOGU: Development and in vitro testing of liposomal gadolinium formulations for neutron capture therapy of glioblastoma multiforme"

Eva Hühn (2008-2013)

"JOGU: Rational design of sustained release liposomal mRNA formulations for parenteral administration and image-guided assessment of in vivo performance"

Robert Winkler (2010-2013)

"JOGU: Konzept eines aktiven Pulverinhalators"

Asma Abdelaziz Salim Radwan (2009-2013)

"JOGU: Biopharmaceutic investigation of negative food effect for BCS class III compounds in solid dosage forms"

Zuheir Abdelrahman Elawad Osman (2009-2012)

"JOGU: Investigation of different shellac grades and improvement of release from air suspension coated pellets"

Karl Buch (2005-2011)

"JOGU: Lanthanide-loaded nanoparticles as a novel radioenhancer in radiation therapy of cancer"

Lukas Mühlfeld (2008-2011)

"JOGU: Einflüsse von Folienqualität und Blister-Design auf die Funktionalität von Blisterverpackungen"

Andrea Hartung (2008-2011)

"JOGU: Prozess Analytische Technologien „PAT“ zur Optimierung von Wirbelschichtgranulationsprozessen"

Olga Pfeifer-Lehmann (2006-2010)

"JOGU: Untersuchung der Adhäsionskräfte in interaktiven Pulvermischungen zur Inhalation und deren Veränderung in Abhängigkeit von der Dichtigkeit der Verpackung"

Markus Jahn (2004–2009)

"JOGU: Struktur, Stabilität, Toxizität und zelluläre Aufnahme von Eisenoxid- und Eisenhydroxid Nanopartikeln"

Gamal Shazly (2005-2009)

"JOGU: Effect of drug physicochemical properties on the release from liposomal systems in vitro and in vivo"

Stefan Grube (2005-2008)

"JOGU: Excipient- and food-drug interactions with spezial emphasis on trospium"

Claudius Weiler (2004-2008)

"JOGU: Generierung leicht dispergierbarer Inhalationspulver mittels Sprühtrocknung"

Natalie Devi Glube, (2001-2007)

"JOGU: The potential of the human kidney cell line Caki-1, as an in vitro sceening system for drug interactions with organic cation transporters"

N. Ceren Alemdaroglu (2004-2007)

"JOGU: Impact of folate absorption and transport for nutrition and drug targeting"

Marija Tubic-Grozdanis (2003-2007)

"JOGU: Biopharmaceutical characterization of modified-release dosage forms of P-glycoprotein and CYP 3A4 substrates in silico and in humans"

Torsten Mau (1999-2006)

"JOGU: Entwicklung und Charakterisierung von Gassterilisationsprozessen am Beispiel der Oberflächensterilisation mittels Wasserstoffperoxid und Ethylenoxid"

Isabell Andrea Schöttle (2001-2005)

"JOGU: Sprühgetrocknete Polylaktid, Poly(Laktid-co-glycolid) Mikropartikel zur Steuerung der Freisetzung aus pulmonalen Arzneiformen"

Marcus Hans Knöll (2002-2006)

"JOGU: Enteric coated mucoadhesive micropellets in rotary agglomeration process for wet spheronization"

Bianca Beilmann (2003-2006)

"JOGU:Evaluierung und Quantifizierung von Einflussfaktoren auf die aerodynamischen Eigenschaften inhalativer Pulvermischungen"

Monika Ofer (Mainz 2004)

"Modulation of Membrane Transport - A Mechanism to Explain Kinetic Interactions Between Drugs and Flavonoids"

Amal El Saeih Fadl Abou El Ela (Mainz 2003)

"Implications of Physicochemical Parameters for Carrier-Mediated and Passive Membrane Transport for Psychoactive Drugs"

Martin Becker (Mainz 2003)

"Charakterisierung der Arzneistoffabsorption aus flüssigen Externa zur kutanen Anwendung am Tier"

Katharina Brodka-Pfeiffer (Mainz 2003)

"Einfluss von Mikronisierungsprozessen auf die physikochemische Stabilität von Pulvern für Inhalationszwecke. Kriterien für die Auswahl von Konditionierungsparametern."

Daniel Wagner (Mainz 2003)

"Sustained-release formulations for compounds underlying intestinal drug efflux"

Annette Koggel (Mainz 2002)

"Influence of Secretory Transporters on the Intestinal Permeability of Cationic Drugs"